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Question

“Both the strands of DNA are not copied during transcription”.
Choose the correct reasons from the following.

A. If both strands of DNA act as a template, RNA would be coded with different sequences, leading to formation of two different polypeptide chains from the same segment of DNA.

B. If both strands of DNA act as a template, RNA would be coded with different sequences, leading to formation of the same polypeptide chains from the same segment of DNA.

C. If both strands of DNA act as a template for transcription, it simplifies the genetic information transfer machinery.

D. If both strands of DNA act as a template for transcription, it complicates the genetic information transfer machinery.

E. If both strands of DNA act as a template for transcription, dsRNA would be formed which would prevent protein formation.

A
A, B, D are correct and C, E are incorrect
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B
A, D, E are correct and B, C are incorrect
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C
A, C, E are correct and B, D are incorrect
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D
B, D, E are correct and A, C are incorrect
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Solution

The correct option is B A, D, E are correct and B, C are incorrect
Statements A, D and E are correct and B, C are incorrect.
Transcription is copying information from one strand of DNA into RNA.
Both strands of DNA cannot act as a template for transcription because of the following reasons:

i. It would code for RNA molecules with different sequences, leading to formation of two different polypeptide chains from the same segment of DNA.

ii. The same segment of DNA providing two pieces of information by coding for different polypeptide chains would complicate the genetic information transfer machinery.

iii. The two RNA strands formed would be complementary to each other and would form a double stranded RNA.

iv. A double stranded RNA (dsRNA) would not be able to get translated into proteins and thus the entire process would become futile.

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