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Question

If adenine makes 30% of the DNA molecule, what will be the percentage of thymine, guanine and cytosine in it?

A
T:20;G:25;C:25
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B
T:20;G:30;C:20
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C
T:20;G:20;C:30
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D
T:30;G:20;C:20
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Solution

The correct option is D T:30;G:20;C:20
According to Chargaff's rule,
[A] = [T], [G] = [C].

[A] + [G] = [C] + [T]
Purines = Pyrimidines.

Total content of DNA = 100 %

[A] + [T] + [G] + [C] = 100%

[A] = 30 % (information given in the question) and hence [T] = 30%

Hence, [G] + [C] + 30% + 30 % = 100 %

[G] + [C] = 100 % - 60 % = 40 %

[G] + [C] = 40 %

Since, [G] = [C]

40/2 = 20%

Hence, [G] = [C] = 20 %

Therefore, A - 30 %, T - 30 %, G - 20%, C - 20%

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