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Question

In a 125 amino acid sequence, if 25th amino acid is mutated to UAA, then

A
A polypeptide of 124 amino acids is formed.
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B
A polypeptide of 25 amino acids is formed.
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C
A polypeptide of 24 amino acids is formed.
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D
Any of the above can be possible.
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Solution

The correct option is C A polypeptide of 24 amino acids is formed.
UAA is a stop codon. It does not code for any amino acid and, therefore, called nonsense codon. Hence, the polypeptide synthesis is terminated and a polypeptide of 24 amino acids is formed. The polypeptide chain of 124 amino acids is formed only when the 125th codon works as a stop codon.
So, the correct answer is 'A polypeptide of 24 amino acids is formed'.

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