The major pollutants to deplete ozone are

The correct option is A Chlorofluorocarbons
Pollution leads to the addition of harmful components in the environment which adversely affect the quality of the environment. CFCs is an organic compound and a volatile derivative of methane, ethane, and propane. It is known as Freon. They are used as a refrigerant. The radical chlorine escapes from CFC in the presence of UV radiation and is long lived in the upper atmosphere where it catalyzes the conversion of ozone into oxygen molecule.

So, the correct answer is option A.