Genetic disorders are due to alterations or abnormalities in the genome of an organism.
A genetic disorder may be caused by a mutation in a single gene or multiple genes and a change in chromosome number or structure.
It can also cause due to external environmental factors.
The race with most genetic disorders:
The database reports from the Centre for Arab Genomic Studies (CAGS) indicated that Arab countries have the highest rates of genetic disorders in the world.
The main reason is the population of this region is characterized by large family size, high maternal and paternal age, and a high level of inbreeding with consanguinity rates in the range of 25-60%.
Moreover, many genetic disorders such as thalassemia, Wilson’s disease, and Niemann-Pick disease are endemic to the Arab countries.