When the cell has stalled DNA replication, which check point should be predominantly activated ?
A
G1/S
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B
G2/G0
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C
G2/M
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D
M
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Solution
The correct option is AG1/S
Stalled forks activate checkpoint signaling and pause replication. Since, G1/S checkpoint checks DNA damage, cells size prior to S-phase (i.e. DNA replication phase). This checkpoint would be activated by stalled DNA replication fork.