Duchenne Muscular Dystrophy

Q. Sickle cell anaemia is an example of which type of inheritance?

1. Sex-linked inheritance
2. Deficiency disease
3. Autosomal heritable disease
4. Infectious disease

Q. Assertion [A]: Sickle cell anaemia affects only males.
Reason [R]: The mutation occurs at multiple regions in the gene responsible for sickle cell anaemia.

1. Both A and R are true and R is the correct explanation of A
2. Both A and R are true but R is not the correct explanation of A
3. A is true but R is false
4. Both A and R are false

Q. Person ‘A’ is suffering from an inborn error of metabolism due to an autosomal recessive trait. This error results mental retardation in him. Person ‘B’ also have retarded mental development but in this person it is due to trisomy of a particular chromosome.

Select the correct option regarding person ‘A’ and person ‘B’.
[0.7 mark]

1. Person 'A'	Person 'B'
   The responsible gene is located on two non-homologous chromosomes	The disorder is a Mendelian disorder

2. Person 'A'	Person 'B'
   This person lacks a particular pancreatic hormone	This person has three X-chromosomes

3. Person 'A'	Person 'B'
   Defective haemoglobin is forming in this person	This person is sterile female

4. Person 'A'	Person 'B'
   This person is unable to convert phenylalanine into tyrosine	This person has trisomy of chromosome 21

Q. Identify the wrongly matched pair.
(A) Typhoid – Widal test
(B) Plague – Viral disease
(C) Malignant malaria – Plasmodium falciparum
(D) Common cold – Rhinovirus

1. A
2. B
3. C
4. D

Q. Define botulism. Name the bacterium responsible for botulism.

Q. maam muscular dystrophy is since birth or happens later in lifetime of individual?

Q. Progressive degeneration of skeletal muscle, mostly due to genetic disorder occurs in

1. Myasthenia gravis
2. Tetany
3. Muscular dystrophy
4. Osteoporosis
5. Arthritis

Q. Assertion :Non-striated muscles are said to be
voluntary in nature Reason: Non-striated muscles can be moved
according to will

1. If both the assertion and the reson are true and the reason
   is correct explanation of the assertion.
2. If both the assertion and the reson are true but the reason
   is not correct explanation of the assertion.
3. If the assertion is true but the reason is false
4. If both the assertion and reason are false

Q.

Which of the following genetic diseases results from a mutation that prevents protein dystrophin from forming?

1. Myasthenia gravis

2. Duchenne muscular dystrophy

3. Osteoporosis

4. Rheumatoid Arthritis

Q. Repetitive muscular activity at moderate levels, such as weight training, can result in

1. Denervation atrophy
2. Mood swings
3. Muscular hypertrophy
4. A decline in health

Q.

Which of the following genetic diseases results from a mutation that prevents protein dystrophin from forming?

1. Myasthenia gravis

2. Duchenne muscular dystrophy

3. Osteoporosis

4. Rheumatoid Arthritis

Q. Which of the following muscular disorders is inherited?

1. Botulism
2. Tetany
3. Muscular dystrophy
4. Myasthenia gravis

Q. In certain parts of India muscular distrophy is commonly found among the poor people because they eat cheap pulses of

1. Phaseolus mungo
2. Pisum sativum
3. Lathyrus sativus
4. Cicer