Lymphocytes

Q. Cells which produce antibodies are

1. B lymphocytes
2. T lymphocytes
3. thrombocytes
4. eosinophils

Q. Read the following statements regarding spleen and select the correct option :-
(i) Spleen is a large bean-shaped organ which mainly contains lymphocytes and phagocytes
(ii) Spleen is a large reservoir of erythrocytes
(iii) Spleen is a primary lymphoid organ
(iv) Spleen acts as a filter of the blood by trapping blood-borne micro-organisms

1. (i), (ii) and (iv)
2. (ii) and (iv)
3. (i), (ii) and (iii)
4. (i) and (ii)

Q. Haematopoiesis of T lymphocytes begins in ________ and ends in ________.

1. bone marrow; thyroid gland
2. bone marrow; thymus
3. bone marrow; spleen
4. thymus; bone marrow

Q. Which among the following is correct regarding primary and secondary immune responses?

1. Primary response: IgM (High), IgG (Low), High intensity immune response
2. Secondary response: IgM (Low), IgG (High), Low intensity immune response
3. Primary response: IgM (Low), IgG (High), Low intensity immune response
4. Secondary response: IgM (Low), IgG (High), High intensity immune response

Q. Which is the first antibody to be produced in primary response to an antigen?

1. IgM
2. IgG
3. IgA
4. Both a and b

Q.

Which of the following does not occur during the lag period of the primary antibody response?

1. activation of helper T cells
2. class switching to IgG
3. presentation of antigen with MHC II
4. binding of antigen to B-Cell Receptors

Q.

Agranulocytes responsible for immune response of the body are
(a) Basophils (b) neutrophils (c) eosinophils (d) lymphocytes

Q.

Why is it called B Cells?

Q. Haematopoiesis of T-lymphocytes and B-lymphocytes occurs in

Q. Haematopoiesis of T lymphocytes begins in ________ and ends in ________.

1. bone marrow; thyroid gland
2. thymus; bone marrow
3. bone marrow; thymus
4. bone marrow; spleen

Q. Match the following:

$\begin{array}{cc}\text{Column A}& \text{Column B}\\ \text{1. Bone marrow}& \text{p. Secondary lymphoid organ}\\ \text{2. Lymph nodes}& \text{q. Antibody production}\\ \text{3. IgE}& \text{r. Primary lymphoid organ}\\ \text{4. B-lymphocytes}& \text{s. Allergic responses}\end{array}$

1. 1-q, 2-p, 3-s, 4-r
2. 1-r, 2-p, 3-q, 4-s
3. 1-r, 2-p, 3-s, 4-q
4. 1-s, 2-r, 3-q, 4-p

Q. Which of the following is not a granulocyte?

1. Basophils
2. Monocytes
3. Acidophils
4. Neutrophils

Q. Which of the following are involved in body defence?

1. Neutrophils
2. Lymphocytes
3. All the above
4. Macrophages

Q. A patient brought to the hospital with myocardial infarction will be immediately treated with

1. Cyclosporin- A
2. Statins
3. Penicillin
4. Streptokinase

Q.

Antibodies are produced by

1. Erythrocytes

2. Thrombocytes

3. Monocytes

4. Lymphocytes

Q. Identify the human blood cell with its characteristics.

1. B-lymphocyte - Forms 20% of blood cells, involved in immune response
2. Neutrophil - Most abundant blood cell, phagocytic
3. Monocyte - Life span 3 days, produces antibodies
4. Basophil - Secretes serotonin inflammatory response

Q. Cells which produce antibodies are:

1. B-lymphocytes
2. T-lymphocytes
3. Thrombocytes
4. Eosinophils

Q. The maturation of T-lymphocytes occur in the

1. Bone marrow.
2. Spleen.
3. Kidney.
4. Thymus.

Q. Smallest human cells are

1. Leucocytes
2. Erythrocytes
3. Sperms
4. Liver cells

Q. From where do erythrocytes, leuxoc leuc and platelets are released

Q. Assertion :Interferons are a type of antibodies produced by body cells infected by bacteria. Reason: Interferons stimulate inflammation at the site injury.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. Foetal haemoglobin has X affinity for oxygen than that of mother's haemoglobin during gestation. X is

1. same
2. higher
3. lower affinity earlier but higher later.
4. lower

Q. With reference to immune system there are two types of lymphocytes-T-cells and B-cells. Why are these so-named and what is their respective function ?

Q. Histamine and heparin are secreted by

1. Monocytes
2. Neutrophils
3. Eosinophils
4. Lymphocytes
5. Basophils

Q. Find out the wrong match ________________.

1. Eosinophils - allergic response
2. Basophils - secrete histamine and serotonin
3. Monocytes - secrete heparin
4. Lymphocytes - immune response
5. Neutrophils - phagocytic and destroy foreign organisms

Q. Human fetal haemoglobin differs from the adult haemoglobin in that it has

1. Higher affinity for oxygen.
2. Lower affinity for oxygen.
3. Two subunits only.
4. Is glycosylated.

Q. Which of the following cells are associated with immune system of the body?

1. Macrophages
2. Lymphocytes
3. Neutrophils
4. All of the above

Q. Polymorphonuclear leucocytes are

1. Neutrophils
2. T lymphocytes
3. B lymphocytes
4. Monocytes

Q. Match the following.

	List I		List II
A	Neutrophil	1	Single large nucleus
B	Eosinophil	2	2 to 3 lobed nucleus
C	Basophil	3	Kidney shaped nucleus
D	Lymphocyte	4	2 to 7 lobed nucleus
E	Monocyte	5	Bilobed nucleus

1. A- 4, B- 5, C- 2, D- 1, E- 3
2. A- 1, B- 4, C- 3, D- 2, E- 5
3. A- 4, B- 1, C- 3, D- 5, E- 2
4. A- 2, B- 5, C- 1, D- 4, E- 3
5. A- 2, B- 4, C- 5, D- 3, E- 1

Q. Antibodies are proteins secreted by

1. memory T cells
2. cytotoxic T cells
3. helper T cells
4. plasma B cells