Turner Syndrome

Q. Mr. Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be the proportion of Bd in his sperms?

1. 0
2. 1/4
3. 1/2
4. 1/8

Q. Match the items of column I with column II:

$\begin{array}{cccc}& \text{Column I}& & \text{Column II}\\ \text{(a)}& \text{XX-XO method of sex determination}& \text{(i)}& \text{Turner's syndrome}\\ \text{(b)}& \text{XX-XY method of sex determination}& \text{(ii)}& \text{Female heterogametic}\\ \text{(c)}& \text{Karyotype-45}& \text{(iii)}& \text{Grasshopper}\\ \text{(d)}& \text{ZW-ZZ method of sex determination}& \text{(iv)}& \text{Female homogametic}\end{array}$

Select the correct option from the following.

1. a-ii, b-iv, c-i, d-iii
2. a-i, b-iv, c-ii, d-iii
3. a-iii, b-iv, c-i, d-ii
4. a-iv, b-ii, c-i, d-iii

Q.

What is hemizygous?

Q. Study the human karyotype given below and identify the disorder:

1. Down’s syndrome
2. Turner’s syndrome
3. Klinefelter’s syndrome
4. The karyotype is of a normal individual

Q. The genotype of an individual with Turner syndrome is:

1. 44 autosomes + XXX
2. 44 autosomes + XO
3. 21 trisomy with XY
4. 44 autosomes + XXY

Q. What is aneuploidy? Name a chromosomal disorder in humans caused due to (a) gain of an autosome, and (b) loss of a sex chromosome in females. [2 marks]

Q.

What is Jacobs syndrome?

Q.

What is the difference between turner syndrome and mosaic turner syndrome?

Q.

Why cant males have Turners syndrome?

Q. Match the items of column I with column II:

$\begin{array}{cccc}& \text{Column I}& & \text{Column II}\\ \text{(a)}& \text{XX-XO method of sex determination}& \text{(i)}& \text{Turner's syndrome}\\ \text{(b)}& \text{XX-XY method of sex determination}& \text{(ii)}& \text{Female heterogametic}\\ \text{(c)}& \text{Karyotype-45}& \text{(iii)}& \text{Grasshopper}\\ \text{(d)}& \text{ZW-ZZ method of sex determination}& \text{(iv)}& \text{Female homogametic}\end{array}$

Select the correct option from the following.

1. a-ii, b-iv, c-i, d-iii
2. a-i, b-iv, c-ii, d-iii
3. a-iv, b-ii, c-i, d-iii
4. a-iii, b-iv, c-i, d-ii

Q. Mrs. Verma has an autosomal gene pair "Bb" and she contain x-linked gene "d". What is the percentage of gamete, which contain "bd" gene ?

1. 50 %
2. 25 %
3. 75 %
4. 100 %

Q.

What are the three types of down syndrome?

Q. The chromosomal condition in Turner's syndrome is

1. 21 trisomy with XY
2. 44 autosomes + XXY
3. 18 trisomy with XY
4. 44 autosomes + XXX
5. 44 autosomes + XO

Q.

Choose the correct option regarding the Assertion and Reason:

Assertion [A]: Turner syndrome occurs only in females.

Reason [R]: Turner syndrome is characterised by X0 sex chromosomes.

1. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

2. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

3. Assertion [A] is True and Reason [R] is False.

4. Reason [R] is True and Assertion [A] is False

Q. How many of the following disorders can be classified as chromosomal disorders?
Sickle-cell anaemia, Turner’s syndrome, Cri-du-chat syndrome, Edwards syndrome

1. 1
2. 2
3. 3
4. 4

Q.

What are the characteristics of down’s syndrome?

Q.

What are the different types of Turner syndrome?

Q. An abnormal human baby with 'XXX' sex chromosomes was born due to

1. Fusion of two ova and one sperm
2. Fusion of two sperms and one ovum
3. Formation of abnormal sperms in the father
4. Formation of abnormal ova in the mother

Q. Study the human karyotype given below and identify the disorder:

1. Down’s syndrome
2. Turner’s syndrome
3. Klinefelter’s syndrome
4. The karyotype is of a normal individual

Q. Phenotypically, females having rudimentary ovaries, underdeveloped breasts, short stature, webbed neck, often with subnormal intelligence suggest:

1. Down’s syndrome
2. Klinefelter’s syndrome
3. Turner’s syndrome
4. Haemophilic syndrome

Q. Down’s syndrome is caused due to

1. trisomy of X chromosome
2. monosomy of X chromosome
3. trisomy of ${18}^{th}$ chromosome
4. trisomy of ${21}^{st}$ chromosome

Q. A human female with Turner's syndrome :

1. Is able to produce children with normal husband
2. Has one additional X chromosomes
3. Exhibits male characters
4. Has 45 chromosomes with XO

Q.

Why is Down syndrome not curable?

Q. Examples of congenital diseases are

1. Alkaptonuria, albinism
2. Albinism, sickle cell anaemia
3. Haemophilia
4. All of the above

Q. What is not correct with regard to Klinefelter’s syndrome?

1. Testes are reduced
2. Genitalia is like that of males
3. Genetic constitution is like normal female
4. Ovaries may be present in rudimentary state

Q. What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia and is sterile?

1. Down's syndrome
2. Turner's syndrome
3. Klinefelter's syndrome
4. Edward's syndrome

Q.

Choose the correct option regarding the Assertion and Reason

Assertion [A]: Turner’s Syndrome occurs only in females.

Reason[R]: Turner’s Syndrome is characterized by XO sex chromosome.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False

3. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

4. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

Q. Mr. Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be the proportion of Bd in his sperms?

1. 0
2. 1/4
3. 1/2
4. 1/8

Q. A marriage between a colourblind man and a normal woman produces _______________.

1. 50% Colourblind sons, 50% normal sons
2. 50% Carrier daughters, 50% normal daughters
3. All carrier daughters and normal sons
4. All carrier off springs

Q. Jay has been diagnosed with a mitochondrial disease. His wife does not have the disease and currently is pregnant. What is the risk that this child will have the disease?

1. 50%
2. 0%
3. 25%
4. 100%