Inheritance of Autosomal Dominant Disorders

Q.

Neurofibromatosis is a disease that affects both males and females. It causes nerve endings to form a tumorous growth that swells up in size. There is no affinity towards any sex. Also, if one of the parents has it, there is 50% chance that the offspring will suffer from it. What kind of disease is this?

1. Autosomal Dominant

2. X-Linked Recessive

3. Autosomal Recessive

4. X-Linked Dominant

Q.

Regarding the assertion and reason, choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.
Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False.

3. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Q.

Neurofibromatosis is a disease that affects both males and females. It causes nerve endings to form a tumorous growth that swells up in size. There is no affinity towards any sex. Also, if one of the parents has it, there is 50% chance that the offspring will suffer from it. What kind of disease is this?

1. Autosomal Dominant

2. X-Linked Recessive

3. Autosomal Recessive

4. X-Linked Dominant