A change in the amount of yolk and its distribution in the egg will affect

The correct option is D Pattern of cleavage
Post fertilisation, the pattern of cleavage is affected by amount of yolk. Many animal eggs contain yolk, a mixture of proteins, phospholipids, and fats that serves as food for the developing embryo. The amount and distribution of yolk vary among different animal groups, depending on the needs of the embryo. Mammalian eggs have very little yolk, because the embryo obtains maternal nutritional support throughout most of its development, whereas the eggs of birds and reptiles must contain sufficient yolk to sustain the embryo until hatching.

Therefore, the correct answer is option C.