A couple, both carriers for the gene sickle cell anaemia planning to get married, wants to know the chances of having anaemic progeny?
A
100%
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B
75%
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C
50%
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D
25%
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Solution
The correct option is D25% Sickle cell anemia is an autosomal recessive trait. Since the father and mother both are carriers, only 1 out of the 4 children is affected. Thus the probability of having an anemic progeny is 25%. Thus the correct answer is option D.