A couple, both carriers of the gene responsible for sickle-cell anemia, is planning to get married and wants to know the chances of their children inheriting the disease.
A
100%
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B
75%
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C
50%
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D
25%
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Solution
The correct option is D
25%
Sickle-cell anaemia is an autosomal recessive trait which gets transmitted from parents to offsprings. If both the parents are carriers for the gene, then only the child inheriting the defective gene from both the parents will inherit the disease.