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Question

A heterozygous carrier of the hemophilia allele in woman marries with a man who is affected with hemophilia. What will be the expected percentage of hemophilia in their female children?

A
0%
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B
25%
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C
50%
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D
75%
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E
100%
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Solution

The correct option is C 50%
genotype Xh X
Xh
Xh Xh XhX
Y XhY XY
Colour blindness is X-linked recessive disease, which influences the man when present in X chromosome; Y chromosome does not carry any genes. Whereas in females it influences only in homozygous condition. According to the question The woman is a carrier i.e., XXh and man is affected i.e., XhY and the cross between the two will result in 50% of the daughters affected according to punnet square. Thus, the correct answer is option C.



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