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Question

A man with blood group A marries a woman with blood group O and their daughter has group O. Is this information enough to tell you which of the traits-blood group A or O- is dominant?Why or why not?

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Solution

Given information is not sufficient to tell which of the blood is dominant because blood group is determined by multiple alleles ( IA, IB and I ) and each individual have two alleles for blood group. These alleles are segregated during gamete formation and a new combination of alleles after fertilisation determines blood group of offspring.
Hence, a man with blood group A might have genotype IAIA, IAi while a woman with blood group has genotype 'ii'. As their daughter has blood group O, she has genotype ii. This is possible only if the father has genotype IAi. This is because allele IA is dominant over 'i'.



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