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Question

A normal-visioned man whose father was colourblind marries a woman whose father was also colourblind. They have their first child a daughter. What are the chances that this child would be colourblind?

A
25%
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B
50%
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C
100%
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D
0%
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Solution

The correct option is D 0%
Colourblindness is a X-linked recessive disorder. Father transmit its X chromosome to the daughters so the colourblind father will inherit its affected X chromosome to the daughter. Hence, the genotype of carrier female will be (XcX). The father of man was colourblind but that as son don't receive X-chromosome of father, the man will be normal (XY). The carrier female and normal man will inherit the disease to 1 son and no daughter. They have their first child a daughter and there are 0% chances for her to have disease. Correct answer is option D.
Parent generation : "XcX" x "XY"
Gametes :
XcX -->
XY
Xc
X
X
XcX
normal carrier girl

XX
normal girl
YXcY
colourblind boy
XY
normal boy

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