A scientist studying transcription in bacteria discovers a nonsense mutation in the regulatory gene of a repressible operon. The resulting protein products of the gene are non-functional. In the bacteria with this mutation the scientists observes
A
No transcription of the operon associated with the regulatory gene.
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B
RNA polymerase enzymes with non-functional three-dimensional shapes.
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C
Continuous transcription of the operon associated with the regulatory gene.
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D
Ribosomes with non-functional small subunits.
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Solution
The correct option is A No transcription of the operon associated with the regulatory gene. A nonsense mutation is a type of mutation where the polypeptide synthesis is stopped due to the formation of a terminating or nonsense aberration.
most of the time these are the stop codons such as UAA, UAG, UGA.
These would result in termination of the gene as it would not make any protein.
So, the correct option is 'No transcription of the operon associated with the regulatory gene'