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Question

Albinism is an inherited condition caused by a recessive allele a. A is the dominant allele for the normal condition. What are the genotypes of individuals R and S?
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A
R = AA, S=AA
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B
R = AA, S=Aa
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C
R = Aa, S=Aa
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D
R = aa, S=aa
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Solution

The correct option is B R = Aa, S=Aa
  • In generation 1, the albino male and albino female will have their genotype as "aa" (recessive allele for albinism).
  • In an autosomal recessive pedigree, normal male and female may have their genotype as "AA" or "Aa".
  • All children in generation 2 are normal. Hence, their genotypes will be "Aa" because one of their parent is affected and can only transfer recessive allele to their children.
  • In generation 3, there are 7 children (2 normal males, 3 normal females, 1 albino male, and 1 albino female).
  • The genotypes of normal children will be "Aa", whereas that of albino children will be "aa". R and S belong to generation 2, where all the children are normal with their genotype as "Aa".

So, the correct answer is option C.

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