Albinism is known to occur due to an autosomal recessive mutation. The first child of a couple with normal skin pigmentation was an albino. What is the probability that their second child will also be an albino?

100%

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25%

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50%

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75%

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Solution

The correct option is D 25%
Since, the couple has normal pigmentation but their first child has albinism, thus, the genotype of the couple is A Aa (where A is the autosome and Aa is the autosome carrying gene for albinism)
P generation: A Aa X A Aa
F $_{1}$ generation: AA AAa AAa AaAa
(Normal) (Albino)
Normal : Albino = 3 : 1

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