An anticoagulant used for preventing clotting in vitro is sodium oxalate- It prevents clot formation byBlocking the fibrinogen activityGetting itself deposited over the surface of ROCInhibiting clotting factor VIII activityCombining with cations in the blood

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Coagulation Cascade

An anticoagul...

Question

An anticoagulant used for preventing clotting in vitro is sodium oxalate. It prevents clot formation by

Combining with cations in the blood

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Inhibiting clotting factor VIII activity

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Getting itself deposited over the surface of ROC

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Blocking the fibrinogen activity

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Solution

The correct option is D Combining with cations in the blood
Sodium oxalate (like citrates) can be used to remove calcium ions (Ca $^{2 +}$ ) from the blood plasma. The oxalate prevents clotting by forming insoluble calcium salts, thus removing ionic calcium (or cations).
Therefore, the correct answer is option A.

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