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Question

Assertion [A]: Patients suffering from sickle cell anaemia have RBCs looked like sickle shape.

Reason [R]: Sickle cell anaemia occurs due to the substitution of glutamic acid by valine at 6th position of β-chain of haemoglobin.
  1. A is True and R is False
  2. Both A and R are true but R is not a correct explanation to A
  3. R is True and A is False
  4. Both A and R are true and R is a correct explanation for A

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