De Vries theory of mutation is :

The correct option is D Not opposed to natural selection theory.
According to De Vries theory of evolution,

• Mutation or discontinuous variation is the raw material of evolution.
• The mutation appears suddenly and produced their effect immediately.
• Mutants are different from the parents and there is no intermediate stage between the two.
• The same type of mutation can appear in several individuals of a species.
• Mutation can appear in all direction and all mutations are the inheritance
• Useful mutations are selected by nature an lethal mutations are eliminated.

So, the correct option is 'Not opposed to natural selection theory'