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Question

During the growth period, release of too much growth hormone can lead to

A
Cretinism
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B
Acromegaly
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C
Gigantism
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D
Dwarfism
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Solution

The correct option is C Gigantism
An excess of growth hormone during the growing period causes gigantism. The secretion of growth hormone from the anterior pituitary is regulated by the GH-RH from the hypothalamus. An excess of growth hormones affects adults and children differently. Excess secretion of growth hormones in children causes gigantism. This excess in growth hormone leads to excessive linear growth, causing the individual to be very tall, with abnormally large hands and feet and coarse facial features including a prominent forehead and jaw. Growth hormone excess is seen in adults as well and is known as acromegaly. Sufferers of this disease show increased periosteal bone growth, organomegaly, as well as glucose intolerance as growth hormone is responsible for preventing glucose uptake into cells.

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