During which stage splitting of centromere does not occurs?

The correct option is A

Metaphase I.

The correct option is A:

Explanation of the correct option

1. All of the genetic material is condensing into chromosomes during metaphase I of the cell cycle.
2. These chromosomes become visible after that. The nucleus dissolves at this point, and the cell's chromosomes appear in the cytoplasm.

Explanation of the incorrect options

Option B:

1. The chromosomes are positioned in the middle of the cell during metaphase II.
2. There will be no homologues this time. Chromosomes are the condensed DNA genetic structures in cells that hold an organism's genetic information.

Option C:

1. Anaphase I begin when homologous chromosomes separate.
2. Nucleoli reappear when the nuclear envelope reforms.
3. The centrosomes begin to move apart as the chromosomes coil up and the nuclear membrane begins to dissolve.
4. Sister chromatids align to the equator of the cell, and spindle fibers develop.

Option D:

1. The spindle fibers pull the chromatids apart during anaphase II.
2. They are now classed as chromosomes rather than chromatids.
3. The chromosomes are a group of genes that make up a person's DNA.
4. The genetic structures in cells made out of condensed DNA that contain an organism's genetic code.

Final answer:

The splitting of the centromere does not occur in the Metaphase I stage.