Enumerate the various changes that occur in the nucleus of the cell during prophase of mitotic division.

The various changes that occur in the nucleus of the cell during prophase of mitotic division are -

1. Centrioles start moving apart and reach opposite poles.​ (0.5 mark)

2. Chromosomes become distinct.​ (0.5 mark)

3. Chromosomes are already duplicated as paired chromatids.​ (0.5 mark)

4. Sister chromatids attach to each other at a small region called centromere.​ (0.5 mark)

5. Spindle fibres appear between daughter centrioles.​ (0.5 mark)

6. Nuclear membrane and nucleolus disappear. (0.5 mark)