Failure or reduced insulin production causes

The correct option is A Diabetes mellitus

A. Diabetes mellitus occurs when there is increased levels of sugar in blood and this condition is called hyperglycaemia. This disorder is caused due to deficiency or low secretion of insulin hormone.

B. Diabetes insipidus is a disorder in which there is less secretion of ADH due to which there is less water reabsorption in kidneys.

C. Addison's disease is caused due to hyposecretion of steroid hormones from adrenal glands. The steroid hormones are cortisol and aldosterone which are secreted from adrenal cortex.

D. Cushing disease occurs due to hypersecretion of cortisol which is a glucocorticoid hormone secreted from adrenal cortex.

So, the correct answer is 'Diabetes mellitus'.