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Question

Haemophilia and colourblindness are the disorders caused by X chromosome linked recessive gene. A woman has one X chromosome having gene for haemophilia and colourblindness. The other X chromosome has wild allele for both the characters. She marries a man having phenotype normal for both the traits. Which of the following statement is most likely for the progeny?

A
All daughters haemophilic and colourblind.
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B
50% haemophilic sons and 50% colourblind sons.
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C
50% haemophilic colourblind sons and 50% normal sons.
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D
25% haemophilic daughters and 75% colourblind sons
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Solution

The correct option is C 50% haemophilic colourblind sons and 50% normal sons.
The woman is a carrier for both the disorders hemophilia and color blindness and carries these genes on the X chromosome so the genotype of the woman will be Xhc X where h is for hemophilia and c is for color blindness. The genotype of the normal man is XY. The cross between the two will result in the progeny of Xhc X, XX, XY and Xhc Y. So, there are 50% males affected with hemophilia and color blindness and 50% are normal.
Thus, the correct answer is option C.

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