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Question

Identify the mismatched pairs:
DisorderCharacteristic featurei.HaemophiliaSex linked recessiveii.Down's syndromeTrisomy 21iii.Turner's syndromeTrisomy of sex chromosomeiv.Klinefelter's syndromeMonosomy of sex chromosome

A
i, iii
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B
ii, iv
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C
i, ii
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D
iii, iv
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Solution

The correct option is D iii, iv
Haemophilia is a sex-linked recessive genetic disorder (X-linked) which is characterised by impaired blood clotting.

Down’s syndrome is characterised by trisomy of the 21st chromosome (three copies of 21st chromosome instead of two copies per cell). It is a chromosomal disorder.

Turner’s syndrome is characterised by the absence of a copy of the X chromosome in females. A chromosomal disorder in which a single chromosome is missing is called monosomy.

Klinefelter’s syndrome is characterised by the presence of an additional X chromosome in the males. Hence, the affected individuals have three copies of sex chromosomes (XXY) and this condition is called trisomy.

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