The correct option is A pBR322
The pBR322 plasmid is an E. coli vector. It was constructed in the year 1977 in the laboratory of Herbert Boyer. In pBR322, the p stands for "plasmid" and the B and R for "Bolivar" and "Rodriguez", respectively. It is 4361 base pair long and contains ampicillin and tetracycline resistant genes.