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Question

If a colourblind man is married to a normal woman, then from the point of view of disease, their offsprings will be

A
All sons will be colourblind.
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B
All daughters will be colourblind.
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C
All sons and daughters will be normal.
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D
All sons and daughters will be colour blind.
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Solution

The correct option is C All sons and daughters will be normal.
Colour blindness is a X-linked recessive disorder. One copy of the affected gene in males in each cell is sufficient to cause the disorder (XcY). Females with two copies of the affected gene show the disorder (XcXc). Females heterozygous (XcX) for this trait be normal but serve as a carrier of the disease. According to the question, the female is normal (XX) and father is colour blind (XcY). The affected father will inherit the affected allele (XcY) to all daughters who will have normal vision but serve as carrier. Correct answer is option C.
Parent generation : XX x XcY
Gametes :
XX ---->
XcY
X
X
Xc
XcX
carrier girl

XcX
carrier girl
YXY
normal boy
XY
normal boy


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