If both parents are carriers for thalassaemia, which is autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?
A
25%
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B
100%
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C
No chance
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D
50%
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Solution
The correct option is A 25% Suppose, N is the normal gene and NTis the carriers gene for thalassaemia.
Gametes from parents
N
NT
N
NN
NNT
NT
NNT
NTNT
Since thalassaemia is autosomal recessive disorder, the chances (percentage) of pregnancy resulting in an affected child = 14×100% = 25%