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Question

If the frequency of the autosomal dominant allele is 0.6 then calculate the frequency of recessive phenotype in a population of 6000.


A

960.

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B

1000.

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C

1200.

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D

4000.

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Solution

The correct option is A

960.


The correct option is A.

Explanation for the correct option:

  1. Autosomal dominance is an inheritance pattern found in several genetic illnesses.
  2. The term "autosomal" refers to a gene that is found on one of the numbered or non-sexual chromosomes.
  3. "Dominant" denotes a single copy of the illness-causing mutation is enough to induce the condition.
  4. Dominance is not innate in an allele or its characteristics (phenotype).
  5. Any function between two alleles of the same gene has a strictly relative impact; one allele may be dominant over the second allele, recessive over the third, and co-dominant over the fourth.
  6. For one characteristic, one allele may be dominant while the other is not.

Given:

p = 0.6

Formula used:

q = 1 - p

Solution:

q = 1 - 0.6

q = 0.4

q = ( 0.4 )2

So in 6000 individuals,

= 16/ 100 * 1000

= 960.

Final answer: The frequency of recessive phenotype in a population of 6000 is 960


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