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Question

In a human population at Hardy-Weinberg equilibrium, the recessive gene is homozygous in 64% of the population. What will be the frequency of heterozygotes in the population?

A
23%
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B
32%
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C
96%
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D
64%
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Solution

The correct option is B 32%
The frequency of recessive gene is 64% that is 0.64, and it is represented as q2
q= q2 = 0.64= 0.8
Since p + q = 1
p + 0.8 = 1
p = 1 - 0.8 = 0.2

Using the Hardy-Weinberg equation p2+2pq+q2=1,
heterozygotes are represented 2pq
Therefore, 2pq= 2×0.8×0.2
2pq = 0.32 or 32%
So, 32% of the individuals in the population are heterozygous for the given gene.

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