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Question

Is Crohn's disease caused by a frameshift mutation?


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Solution

Frameshift mutation:

  1. A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence.
  2. It changes the way the sequence is read.

Crohn's disease causes:

  1. Crohn's disease is a chronic disorder of the digestive system.
  2. It is caused by a frameshift mutation.
  3. Crohn's disease is caused by the insertion of cytosine in the gene encoding a truncated NOD2 protein.
  4. This truncated NOD2 protein is found to be associated with Crohn's disease.
  5. It is incurable.

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