People who carry an allele for normal haemoglobin and an allele for sickle cell are resistant to malaria. They are example of

Q. $H{b}^{A}andH{b}^s$ alleles of normal and sickle cell haemoglobin are

Q. $H{b}^A$ and $H{b}^S$ alleles of normal and sickle celled RBC are

Q. Assertion :Sickle-cell anemia is a genetically determined disorder affecting many new born babies. Reason: It is caused by heterozygosity for allele Hb${}^s$ producing a single amino acid substitution in the $\alpha$-chain of the normal haemoglobin molecule determined by allele Hb${}^A$.

Q. Haemoglobin of normal and sickle cell patient are subjected to electrophoresis. They will show _____________.

Q. Sickle cell anemia is a genetic disorder caused by a substitution mutation in the gene encoding hemoglobin, the protein on blood cells responsible for carrying oxygen. This mutation causes the hemoglobin protein to fold incorrectly, preventing the protein from carrying oxygen to the red blood cells.
Sickle cell anemia is inherited as a codominant trait, meaning that both alleles are expressed equally and that one is not dominant over the other. The allele for normal hemoglobin is represented by S, and the allele for abnormal hemoglobin is represented by s.
If two heterozygous individuals mate and produce offspring, what proportion of their offspring are expected to have fully sickled red blood cells?