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Question

Pleiotropy is the term that refers to the situation in which a gene influences more than one trait. Its example is given by

A
Sickle cell anaemia
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B
Hemophilia
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C
Colour blindness
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D
Only (a) and (b)
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Solution

The correct option is A Sickle cell anaemia

Pleiotropy occurs when variation at a single gene locus affects multiple aspects of the phenotype. For persons with an HbS/ HBs genotypes, medical consequences include anaemia, damage to various internal organs including the spleen and heart, and a 'tower' or 'bossed skull'.


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