Regarding the assertion and reason, choose the correct option.

Assertion [A]: Individuals affected with phenylketonuria exhibit mental retardation.

Reason [R]: The affected individuals lack an enzyme, phenylalanine hydroxylase which results in accumulation of phenylalanine in the body

Both A and R are correct and R explains A

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Both A and R are correct but R does not explain A

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A is correct and R is incorrect

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Both A and R are incorrect

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Solution

The correct option is A
Both A and R are correct and R explains A

Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine. The affected individuals of phenylketonuria lack phenylalanine hydroxylase that converts phenylalanine into tyrosine. Accumulation of phenylalanine which is converted into phenylpyruvic acid in the brain results in mental retardation.

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Q. Assertion :Phenylpyruvic acid is excreted through urine in case of phenylketonuria. Reason: The affected individual lacks enzyme phenylalanine hydroxylase.

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Reason [R]: Sound levels of jet planes usually exceed 150 dB.

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(a) Both assertion and reason are correct and the reason is correct explanation of assertion
(b) Both assertion and reason are correct, but reason does not explain assertion.
(c) Assertion is correct, but reason is incorrect
(d) Both assertion and reason are incorrect
(e) Assertion is incorrect but reason is correct.

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Reason (R) Order is determined experimentally and molecularity is the sum of the stoichimetric coeffcient of rate determining elementary step.

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Reason (R) We cannot determine order from balanced chemical equation.

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Regarding the assertion and reason, choose the correct option. Assertion [A]: Individuals affected with phenylketonuria exhibit mental retardation. Reason [R]: The affected individuals lack an enzyme, phenylalanine hydroxylase which results in accumulation of phenylalanine in the body

Regarding the assertion and reason, choose the correct option.

Assertion [A]: Individuals affected with phenylketonuria exhibit mental retardation.

Reason [R]: The affected individuals lack an enzyme, phenylalanine hydroxylase which results in accumulation of phenylalanine in the body