Repeated self pollination over the generations produces.

The correct option is D Weak progeny
When there is repeated self pollination, only one type of offsprings are produced which leads to a condition called the inbreeding depression. In inbreeding depression, due to only one type of offsprings, the actual characters are lost which will affect the survival of that particular species. So, as the main and important characters are lost in the progeny, the weak progeny are produced which can't continue to the future generations. This continuously forming same type of offsprings is called the homozygosity which leads to the harmful condition called inbreeding depression.

So, the correct option is D.