The tendency of a population to remain in genetic equilibrium may be disturbed by

The correct option is D Lack of random mating

Genetic equilibrium refers to the condition in a population where the frequency of the gene pool does not change even after the arrival of the next generation. This equilibrium was studied by Hardy and Weinberg, who stated that if there is no mutation, no immigration and emigration on the gene locus, then the frequency of the alleles in a population always remain constant.

Random mating prevents any change in allele frequency, as it increases the heterozygosity among the population.