Universal donor and universal acceptor is:

The correct option is D

O^- and AB⁺

The correct option is D.

Explanation of the correct option:

1. The ability of a substance or equipment to operate in contact with blood without causing unfavourable reactions is known as blood compatibility.
2. Because the O^- lacks both antigens for the blood group and antigens for the Rh factor, it is a universal donor.
3. Because it has no antibodies to A, B, and Rh, the AB^- is a universal acceptor and may absorb red blood cells from any kind of donor.

Explanation of the incorrect option:

Option A:

O⁺ can donate blood only to O⁺, A⁺, B⁺ and AB⁺

Option B:

AB^- can receive blood only from AB^-, A^-, B^- and O^-

Option C:

O⁺ can donate blood only to O⁺,A⁺, B⁺ and AB⁺.

Final answer: Universal donor and universal acceptor is O^- and AB⁺.