What are chromosomal disorders?

Chromosomal disorders:

1. It is a disease that causes deformities or malfunctions in any of the body's systems as a result of an aberrant chromosome number or constitution.
2. Humans have 46 chromosomes grouped into 23 pairs, each of which varies in size and shape and is numbered according to the convention.
3. There are 22 pairs of autosomes, with sex chromosomes accounting for one (number 23).
4. Abnormalities result from deviation from this pattern.
5. A whole set of chromosomal pairs can be duplicated three times or more (polyploidy), or one arm or portion of one arm of a single chromosome can be missing (monosomy) (deletion).
6. Examples include Down syndrome, XYY syndrome, and triple X.
7. Trisomy 18 and 13, and Klinefelter syndrome are other examples.