What are Mendelian disorders? Mention two examples.

Mendelian disorders:

1. Mendel's investigations into the modes of inheritance in pea plants laid the groundwork for the current understanding of single-gene disorders in humans. These illnesses, which are also known as Mendelian or monogenic disorders, are brought on by gene mutations and occasionally run in families.
2. Genetic illnesses result from abnormalities in the genome or gene mutations.
3. These kinds of diseases are caused by mutations in one gene, and they sometimes run in families.
4. Pedigree analyses of large families with many affected individuals can be used to determine whether a disease-associated gene is located on an autosome or on a sex chromosome and whether the related disease phenotype is dominant or recessive.

Examples of Mendelian Disorders in Humans

1. Sickle cell anemia
2. Thalassemia
3. Cystic fibrosis
4. Colour blindness
5. Haemophilia
6. Skeletal dysplasia
7. Muscular dystrophy
8. Phenylketonuria