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Question

What happens when the O2 hb dissociation curve shifts?


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Solution

Dissociation of the curve:

  1. The O2-Hb dissociation curve describes the efficiency of oxy-Hb (oxyhemoglobin) releasing oxygen to tissue cells in the phenomenon of internal respiration, showing a distinctive sigmoid shape.
  2. When the dissociation curve shifts to the right, it results in the Bohr effect, wherein lesser haemoglobin (Hb) saturation takes place.
  3. Here, more oxygen is liberated from oxyhemoglobin.
  4. When the dissociation curve shifts to the left (less likely), it is referred to as the Haldane effect.
  5. Here, more haemoglobin saturation takes place while lesser oxygen is released.

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