What is the cause of the depletion of the ozone layer? How does it affect us?

The depletion of the ozone layer refers to the reduction in the concentration of the ozone layer. It is caused by ozone-depleting substances (ODSs), such as chlorofluorocarbons (CFCs), halons, methyl bromide, nitrogen oxides and chlorine.
Among the most important ozone-depleting substances are CFCs, which are rich in chlorine, fluorine and carbon (such as carbon tetrachloride and dichlorofluoromethane).
Effects of the depletion of the ozone layer:
(i) It causes skin cancer because of excess exposure to UV radiation.
(ii) It damages the eyes and the immune system.
(iii) It affects plants and decreases crop yields.