What is the characteristic feature differentiating secondary follicles from primary follicles?
Primary follicle: It is an immature ovarian follicle surrounded by single layer of cuboidal cells. They are known as granulosa cells.
Secondary follicles: The primary follicle develops into a secondary follicle. It consists of many layers of cuboidal cells known as membrana granulosa cells. It secretes follicular fluid.
Primary follicles | Secondary follicles |
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2. It is a preantral follicle without a cavity filled with fluid. | 2. Similar to the primary follicle, the secondary follicle is devoid of a hollow that is filled with fluid. It is therefore a preantral follicle. |
3. The primary follicle is a tiny follicle with only one layer of follicular cells. | 3. Secondary follicles are structurally bigger than main follicles. |
4. Additionally, it is an immature ovarian follicle with a few specialized epithelial cells around an immature ovum. | 4. The secondary follicle's main oocyte is encircled by granulosa cells in many layers, a basal lamina, and a theca layer. |