Which genetic disorder is caused due to the presence of an additional copy of X-chromosome (A Karyotype of 47, XXY)?

Assertion [A]: Klinefelter syndrome occurs only in males.

Reason [R]: Klinefelter syndrome is characterised by an additional Y chromosome in the karyotype.

Assertion reason type question

Assertion

Klinefelters syndrome shows gynaecomastia

Reason

An additional Y chromosome is present in the karyotype

Mark the odd one w.r.t to syndrome which occur due to failure of segregation of homologous pair of chromosomes during cell division cycle

A) klinefelter syndrome

B) down syndrome

C) turner syndrome

D) thalassemia

Which of the following statement is incorrect?

A. The disorder in Collagen protein may cause "Ehlers-Danlos Syndrome"

B. A4 is the protein that is involved in Alzheimer's disease.

C. A mutation in the alpha chain of haemoglobin is the cause of sickle cell anemia

D. Klinefelter syndrome is a manifestation of XXY chromosome aneuploidy.