Which is an autosomal chromosomal mutational disorder?

The correct option is B Cri-du-chat
Huntington chorea is a neurodegenerative genetic disorder affecting the brain.
A thalassemia is a form of autosomal recessive blood disorder characterised by abnormal formation of haemoglobin.
Jacob syndrome is characterised by an extra copy of Y chromosome in each of a male's cells.
The majority of human chromosomal abnormalities occur in the autosomes and some of which are caused by the mutations.
Cri-du-chat syndrome is a rare genetic disorder due to a missing part caused by the deletion of chromosome 5.
So, the correct answer is option B.