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Question

Which of the following correctly describes the difference between R and S-strains of Streptococcus pneumoniae (pneumococcus) bacteria in Frederick Griffith’s experiment?

A
The S-strain bacteria have a lipid coat while R-strain bacteria have a mucous coat.
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B
The S-strain bacteria have a mucous (polysaccharide) coat while R-strain does not.
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C
Mice infected with the S-strain(virulent) do not develop pneumonia but mice infected with the R-strain(non-virulent) develop pneumonia.
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D
The S-strain bacteria produce rough colonies, while the R-strain produces smooth colonies.
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Solution

The correct option is B The S-strain bacteria have a mucous (polysaccharide) coat while R-strain does not.
The S-strain of Streptococcus pneumoniae (pneumococcus) bacteria in Frederick Griffith’s experiment has a mucous (polysaccharide) coat while the R-strain does not.
Therefore, S-strain bacteria produce smooth shiny colonies while the R-strain produces rough colonies. Mice infected with the S-strain (virulent) died from pneumonia infection but mice infected with the R-strain (non-virulent) did not develop pneumonia.

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