Which of the following has the greatest affinity for haemoglobin?

N_{2}

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N O

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O_{2}

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C O_{2}

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Solution

The correct option is B $N O$
NO binds rapidly to haem iron in Hb and once bound, the NO activity is largely irretrievable, the binding is purportedly so tight as to be unaffected by $O_{2}$ or CO. So, NO has the greatest affinity toward haemoglobin.

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