With regard to insulin choose the correct options:
a) C-peptide is not present in mature insulin.
b) The insulin produced by rDNA technology has C-peptide.
c) The pro-insulin has C-peptide
d) A-peptide and B-peptide of insulin are interconnected by disulfide bridges.
With regard to insulin choose the correct options:
a) C-peptide is not present in mature insulin.
b) The insulin produced by rDNA technology has C-peptide.
c) The pro-insulin has C-peptide
d) A-peptide and B-peptide of insulin are interconnected by disulfide bridges.
The correct option is D (a), (c) and (d) only
The correct option is D.
Explanation of the correct answer:
- Insulin is a hormone made by the pancreas that allows the body to use sugar from carbohydrates for energy.
- It is released into the bloodstream to lower the level of glucose in the blood.
- Insulin is made up of 2 chains: A and B-peptides, which are joined by disulfide bonds.
- Insulin is synthesized as a prohormone in mammals which needs to be processed before becoming a fully functional hormone.
- Pro-insulin has an extra stretch called the C-peptide.
- The C-peptide is removed when it matures into insulin.
Explanation of the incorrect options:
Option A:
While statement (c ) is correct, statement (b) is incorrect as only A-peptide and B-peptide are present in insulin produced by rDNA technology.
Option B:
Statements (a) and (d) are correct but (c ) is also correct.
Option C:
While statement (d) is correct, statement (b) is incorrect as only A-peptide and B-peptide are present in insulin produced by rDNA technology.
Final answer: C-peptide is absent in mature insulin. The pro-insulin has C-peptide. A-peptide and B-peptide of insulin are interconnected by disulfide bridges are the correct statements concerning insulin.
(a), (c) and (d) only
The correct option is D.
Explanation of the correct answer:
- Insulin is a hormone made by the pancreas that allows the body to use sugar from carbohydrates for energy.
- It is released into the bloodstream to lower the level of glucose in the blood.
- Insulin is made up of 2 chains: A and B-peptides, which are joined by disulfide bonds.
- Insulin is synthesized as a prohormone in mammals which needs to be processed before becoming a fully functional hormone.
- Pro-insulin has an extra stretch called the C-peptide.
- The C-peptide is removed when it matures into insulin.
Explanation of the incorrect options:
Option A:
While statement (c ) is correct, statement (b) is incorrect as only A-peptide and B-peptide are present in insulin produced by rDNA technology.
Option B:
Statements (a) and (d) are correct but (c ) is also correct.
Option C:
While statement (d) is correct, statement (b) is incorrect as only A-peptide and B-peptide are present in insulin produced by rDNA technology.
Final answer: C-peptide is absent in mature insulin. The pro-insulin has C-peptide. A-peptide and B-peptide of insulin are interconnected by disulfide bridges are the correct statements concerning insulin.
